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IMPROVING THE ACCURACY AND PRECISION OF PREDICTIONS OF TFM-NICLOSAMIDECONCENTRATIONS FOR TREATMENT OF SEA LAMPRY SPAWNING TRIBUTARIES

Predicting safe yet effective treatment concentrations of lampricides  is critical to suppressing sea lamprey populations below target  levels.  The toxicity of TFM is influenced by pH and alkalinity via  separate mechanisms.  Bioassays testing the toxicity of  TFM/niclosamide combinations while controlling for both pH and  alkalinity have never been conducted.  That lack currently limits the  development of improved models to predict LC99.9 from stream pH and  alkalinity.  This study will test assumptions about the separate modes  of pH and alkalinity in toxicity of TFM and niclosamide.  The toxicity  of TFM and niclosamide formulations will be tested at the middle and  extremes of combinations pH and alkalinity that are encountered in sea  lamprey spawning streams.  This study would cover the gap between two  previous bioassays.  Results from the second set of bioassays indicate  that 5 % reductions in prediction errors are possible.  We will test  that hypothesis using Bayesian statistical models for prediction of  the LC99.9 of TFM and niclosamide formulations based on the two large  historic bioassays.  Those models will be validated using the data  from the proposed bioassay.  Stream treatment charts will be updated  based on any demonstrated improvements in the precision and accuracy  of LC99.9 predictions.

Status
In progress
Type
Project
Start Date
End Date
Researchers
Steve GutreuterPrincipal Investigator
Associated with 1 projects
Terry BillsResearcher
Associated with 1 projects
Bradley CarlinResearcher
Associated with 1 projects
Agencies
Great Lakes Fishery Commission $ 42,410.00USDActual

Funding 54 projects for a total of $5,089,137.00
Scope of Study
Laboratory Investigation
Theoretical
Scale of Phenomena
Organism
Impact of Pollutants
Exotic Species
Processes
Treatment / Manufacturing Processes
Resource Management
Fisheries
Lake Basin Connecting Channels
Lake Erie
Lake Huron
Lake Michigan
Lake Ontario
Lake Superior
State Province
Michigan
Minnesota
Wisconsin
Biology And Life History
Environmental Requirements / Tolerance
Control And Mitigation
Chemical Measures
Ecosystem Effects
Community Structure
Socio-economic Consideration and Analysis
Resource Management Issues
Annex Numbers
Research & Development
Annex 17
Impact of water quality and AIS on fish and wildlife populations and habitats
General
Aquatic Nuisance Species
Annex
  • Annex Numbers
    Annex Numbers
    Research & Development
  • Annex 17
    Annex 17
    Impact of water quality and AIS on fish and wildlife populations and habitats

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