The study will investigate lesions that are induced specifically by PCB and PCDD congeners, which could impact both humans and wildlife species residing in the Great Lakes basin. It will determine the effects of dioxin and PCBs on maxillary and mandibular squamous epithelia development in mink and mice. Environmentally relevant concentrations of contaminants will be used. As a result, the information will help in the understanding of this effect and its potential impact on humans and wildlife in the Great Lakes basin.
TCDD and PCB 126-Induced Proliferation of Maxillary and Mandibular Squamous Epithelia
Hazardous Polluting Substances - lists
Persistent Toxic Substances
Research & Development
Specific Objectives for toxic substances and effluents
Surveillance and Monitoring