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Is the thyroid status of wild-fish impaired in the Great Lakes' Areasof Concern?

As part of a broader assessment of wildlife health in Great Lakes'  Areas of Concern (AOCs) we are examining wild-fish for evidence of  exposure to thyroid disruptors. Thyroid microfollicular hyperplasia  was a continuing problem in Great Lakes salmonids as recently as   1995.     We divide each AOC into upstream, impact zone, and downstream  sites. At each site, we capture adult males and females of a pelagic  and a benthic species. We assess the external and internal state of  the fish by visual estimation of malformations such as lesions,  tumours, parasites, and eroded fins (DELTs).  We use a suite of   assays to detect perturbations in the thyroid axis.  Those assays   can detect changes in the production of T4 (thyroxine) and in the   peripheral production of T3 (tri-iodothyroxine) from T4.  T4 and T3   de-iodinase activity are measured in liver microsomal fractions. We   measure thyroid epithelial cell height and assessed follicular   condition in slices through that gland.

Status
In progress
Type
Project
Start Date
End Date
Researchers
Mark McMasterPrincipal Investigator
Associated with 2 projects
Agencies
GLAP $ 80,000.00CADEstimates

Funding 2 projects for a total of $160,000.00
Scope of Study
Field Investigation
Scale of Phenomena
Organism
Impact of Pollutants
Toxic Organics
Resource Management
Fisheries
Lake Basin Connecting Channels
Detroit River
Lake Erie
Lake Huron
Lake Ontario
Lake Superior
Niagara River
St. Clair River
State Province
Ontario
Annex Numbers
Research & Development
Annex 17
Impact of water quality and AIS on fish and wildlife populations and habitats
Pollution exchange between AOCs and open lakes
General
Annex
  • Annex Numbers
    Annex Numbers
    Research & Development
  • Annex 17
    Annex 17
    Impact of water quality and AIS on fish and wildlife populations and habitats
    Pollution exchange between AOCs and open lakes

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