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Environmental Endocrine Disrupters: Isolation and identification for bio assessment

These studies deal with isolation, identification and investigation   of the toxicological effects of endocrine disrupting chemicals and   their influence on aquatic system. It involves the development of   new   techniques to identify these priority chemicals. This work supports   Environment Canada's risk assessment and risk management activities.   The department uses this knowledge to make decision on various   initiatives such as Pest Control Products Act, Priority initiatives,   Toxic Substances Management Policy and Canadian Environmental   Protection Act. Test biological activity of herbicides,   insecticides,   fungicides and study their effects on the immune system of fish.   This   study investigates the biological activity of several herbicides,   insecticides, fungicides and their effects on immune system of fish.   The pesticides selected for this study are member of a class of   chemicals that share the characteristic ability to alter, or   disrupt,   the body's hormone or endocrine system. The data suggest that   exposure of fish to these pesticides may alter the innate killing   mechanisms of macrophages, rendering the host more susceptible to   infectious disease. The data is particularly relevant for gill   macrophages that may be directly exposed to these chemicals. The   findings from this study are novel, and to date little is known   about   the modulatory effects of these pesticides on the immune system of   fish. This information will be essential for assessing environmental   impacts of these pesticides on fish populations, and help support   regulatory decisions to either justify or limit their usage.

Status
In progress
Type
Project
Start Date
End Date
Agencies

Funding 13 projects for a total of $134,000.00
Scope of Study
Field Investigation
Laboratory Investigation
Impact of Pollutants
Toxic Organics
Lake Basin Connecting Channels
Lake Erie
State Province
Ontario
Annex Numbers
Pollution from Non-Point Sources
Research & Development
Annex 17
Cause-effect inter-relationships of productivity and ecotoxicity
Impact of water quality and AIS on fish and wildlife populations and habitats
General
Annex
  • Annex Numbers
    Annex Numbers
    Pollution from Non-Point Sources
    Research & Development
  • Annex 17
    Annex 17
    Cause-effect inter-relationships of productivity and ecotoxicity
    Impact of water quality and AIS on fish and wildlife populations and habitats

The Great Lakes - St. Lawrence Research Inventory is an
interactive, Internet-based, searchable database created as a tool to collect and disseminate
up-to-date information about research projects in the
Great Lakes - St. Lawrence Region.