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Identification, Characterization and Inventory of Novel Freshwater Biotoxins

This project is part of the NOAA Oceans and Human Health Initiative   external research grants funding program.  This project will   establish facilities and materials to support a major interest of   the NOAA Oceans and Human Health Initiative Center at the NOAA Great   Lakes Environmental Research Laboratory (GLERL).  Freshwater   biotoxins are markedly understudied relative to those in marine   systems: indeed only microcystins produced by Microcystis spp. are   currently addressed in any federally funded program on the   Laurentian Great Lakes. Recent evidence, however, dictates that   biotoxins both new to science (e.g., ß-N-methylamino-L-alanine or   BMAAs) as well as biotoxins new to the Great Lakes   (cylindrospermopsin, anatoxin-a) have been present in this system in   recent years.  Moreover, strains of freshwater plankton (e.g.,   Planktothrix spp., Anabaena spp.) which were previously thought to   be a toxigenic in the Great Lakes have been shown to produce these   potent toxins.     The project investigators will establish a line of research that   parallels and expands the current GLERL investigation of Microcystis   spp. and microcystins: the investigators will collect and   characterize (using biochemical and genetic tools) novel toxigenic   cyanobacteria from the Laurentian Great Lakes as well a other   freshwater systems, establish molecular and biochemical diagnostics   for their presence and the presence of these specific toxins, and   generate a series of toxin and cell standards (which are currently   unavailable) to be used by GLERL and other researchers. 

Status
In progress
Type
Project
Start Date
End Date
Researchers
Gregory L. BoyerPrincipal Investigator
Associated with 2 projects
Steven WilhelmResearcher
Associated with 2 projects
Agencies
NOAA - National Ocean Service $ 748,921.00USDEstimates

Funding 3 projects for a total of $1,518,926.00
Scope of Study
Field Investigation
Laboratory Investigation
Scale of Phenomena
Biochemical
Cellular
Organism
Processes
Natural Ecological Processes
Lake Basin Connecting Channels
Lake Erie
Lake Huron
Lake Michigan
Lake Ontario
Lake Superior
State Province
Illinois
Indiana
Michigan
Minnesota
New York
Ohio
Ontario
Pennsylvania
Wisconsin
Annex Numbers
Pollution from Non-Point Sources
Research & Development
Specific Objectives for toxic substances and effluents
Annex 17
Ecotoxicity and toxicity effects of pollutants related to developing Annex 1 specific objectives
General
Annex
  • Annex Numbers
    Annex Numbers
    Pollution from Non-Point Sources
    Research & Development
    Specific Objectives for toxic substances and effluents
  • Annex 17
    Annex 17
    Ecotoxicity and toxicity effects of pollutants related to developing Annex 1 specific objectives

The Great Lakes - St. Lawrence Research Inventory is an
interactive, Internet-based, searchable database created as a tool to collect and disseminate
up-to-date information about research projects in the
Great Lakes - St. Lawrence Region.