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Genetic population structure of marine viral haemorrhagic septicaemia virus (VHSV)

The nucleotide sequences of a specific region of the nucleoprotein   gene were compared in order to investigate the genetic population   structure of marine viral haemorrhagic septicaemia virus (VHSV).   Analysis of the sequence from 128 isolates of diverse geographic and   host origin renders this the most comprehensive molecular   epidemiological study of marine VHSV conducted to date. Phylogenetic   analysis of nucleoprotein gene sequences confirmed the existence of   the 4 major genotypes previously identified based on N- and   subsequent G-gene based analyses. The range of Genotype I included   subgroups of isolates associated with rainbow trout aquaculture   (Genotype Ia) and those from the Baltic marine environment (Genotype   Ib) to emphasise the relatively close genetic relationship between   these isolates. The existence of an additional genotype circulating   within the Baltic Sea (Genotype II) was also confirmed. Genotype III   included marine isolates from around the  British Isles in addition   to those associated with turbot mariculture, highlighting a   continued risk to the development of this industry. Genotype IV   consisted of isolates from the marine environment in North America   and the Great Lakes.     Taken together, these findings suggest a marine origin of VHSV in   rainbow trout aquaculture. The implications of these findings with   respect to the future control of VHSV are discussed. The capacity   for molecular phylogenetic analysis to resolve complex   epidemiological problems is also demonstrated and its likely future   importance to disease management issues highlighted.    (VHS); (VHSv); (viral hemorrhagic septicemia); (viral haemorrhagic   septicaemia); (viral hemmorrhagic septicemia)

In progress
Start Date
End Date
M. SnowPrincipal Investigator
Associated with 2 projects
M. SnowResearcher
Associated with 2 projects
Scottish Government/EU $ 0.00USDEstimates

Funding 2 projects for a total of $0.00
Scope of Study
Laboratory Investigation
Impact of Pollutants
Exotic Species
Resource Management
Resource Being Monitored
Beneficial Use Impairment Assessments
Fish Tumours or Other Deformities
Loss of Fish and Wildlife Habitat
Tainting of Fish and Wildlife Populations
Biology And Life History
Parasites and Diseases
Annex Numbers
Research & Development
Annex 17
Impact of water quality and AIS on fish and wildlife populations and habitats
  • Annex Numbers
    Annex Numbers
    Research & Development
  • Annex 17
    Annex 17
    Impact of water quality and AIS on fish and wildlife populations and habitats

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