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Immunoaffinity: A Novel Approach for Identifying Biologically Active Environmental Estrogens in Great Lakes Coastal Estuaries

Estrogens and estrogen-mimics accumulate in aquatic environments  though wastewater effluents, pesticides, detergents and other common  trappings of human activity. Researchers plan to create a new way to  capture estrogen-like compounds from water samples using resin  composed of tiny glass beads coated with cloned estrogen receptors.  This resin will bind with a broader variety of estrogen mimics and  will be more economical to use than current methods for quantifying  environmental estrogens. After perfecting the estrogen extraction  process, the researchers will analyze water from five estuaries  around the Great Lakes, including the Duluth-Superior Harbor.  Hormone imbalances created by environmental estrogens can harm  reproductive and immune systems and lead to deformities and  sterilization in animals.

Status
In progress
Type
Project
Start Date
End Date
Researchers
Deborah SwackhamerPrincipal Investigator
Associated with 7 projects
Agencies
Minnesota Sea Grant College Program $ 82,000.00USDEstimates

Funding 30 projects for a total of $2,568,917.00
Scope of Study
Field Investigation
Laboratory Investigation
Scale of Phenomena
Biochemical
Organism
Land Use and Habitat
Wetlands
Resource Management
Fisheries
Wildlife
Lake Basin Connecting Channels
Lake Superior
State Province
Minnesota
Annex Numbers
Research & Development
Annex 17
Control technologies for treatment of municipal and industrial effluents/emissions
General
Annex
  • Annex Numbers
    Annex Numbers
    Research & Development
  • Annex 17
    Annex 17
    Control technologies for treatment of municipal and industrial effluents/emissions

The Great Lakes - St. Lawrence Research Inventory is an
interactive, Internet-based, searchable database created as a tool to collect and disseminate
up-to-date information about research projects in the
Great Lakes - St. Lawrence Region.