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The study design is a cross-sectional and longitudinal observational   assessment of the effects of PCB exposure, both current and in   utero, on reproductive health. The main goal of this project is to   assess fecundability and reproductive success in two cohort studies   of individuals selected from two source populations at elevated risk   of exposure to PCBs via consumption of Great Lakes sport-caught   fish. A secondary goal is to pilot a case control study of low sperm   count in relation to the same exposures. In the two cohort studies,   investigators aim to examine specific hypotheses about the   relationship of PCB exposure to reproductive health occurring   directly through consumption of sport-caught Great Lakes fish, and   occurring indirectly through in utero exposure. PCB exposure, in   both the cohort and case-control studies will be assessed by a   detailed questionnaire on fishing practices and through serum   analysis for PCBs.     (PCB); (PCB's); (PCBs); (organochloride); (organochlorides); (flame   retardants); (flame retardant); (polychlorinated biphenyls);   (polychlorinated biphenyl); (POPs); (POP); (POP's); (persistent   organic pollutant); (persistent organic pollutants); (toxic   organic); (toxic organics); (human health); (fish consumption);   (restrictions on fish consumption); (chemicals of concern);   (chemical of concern)

Status
In progress
Type
Project
Start Date
End Date
Scope of Study
Laboratory Investigation
Scale of Phenomena
Biochemical
Organism
Physical/Chemical
Resource Management
Fisheries
Lake Basin Connecting Channels
Lake Erie
Lake Huron
Lake Michigan
State Province
Michigan
Beneficial Use Impairment Assessments
Restrictions on Drinking Water Consumption or Taste and Odour Problems
Tainting of Fish and Wildlife Populations
Annex Numbers
Persistent Toxic Substances
Research & Development
Specific Objectives for toxic substances and effluents
Annex 17
Population-based studies on long-term, low-level effects of toxic substances on human health
General
Monitoring
Annex
  • Annex Numbers
    Annex Numbers
    Persistent Toxic Substances
    Research & Development
    Specific Objectives for toxic substances and effluents
  • Annex 17
    Annex 17
    Population-based studies on long-term, low-level effects of toxic substances on human health

The Great Lakes - St. Lawrence Research Inventory is an
interactive, Internet-based, searchable database created as a tool to collect and disseminate
up-to-date information about research projects in the
Great Lakes - St. Lawrence Region.