Skip to main content
hyi
Banner
banner
bn

Endocrine Disrupting Chemicals and Thyroid Outcomes

This study will examine long-term and recent fish consumption in an   existing, well-characterized cohort of 4,2 6 frequent and infrequent   Great Lakes sport fish consumers and will expand biomonitoring from   the original 538 members of the cohort to include 5   additional   members. Dietary exposure to polychlorinated biphenyls (PCBs) may co-  vary with exposure to related chemicals such as polybrominated   diphenyl ethers (PBDEs) and dichlorodiphenyltrichloroethane (DDT).   The effects of these chemicals on thyroid hormone balance will be   determined and the impact of reproductive health and other potential   confounding variables on these relationships characterized.    PBDEs have recently been identified in sport fish from Lake Michigan   at among the highest observed levels worldwide and may be   increasing. The objective of this study is to characterize exposures   to these chemicals and other relevant variables and to determine   mechanisms by which PBDEs in Great Lakes fish may act separately or   synergistically with PCB exposure to impair thyroid function.    (fish consumption); (restrictions on fish consumption); (human   health); (polychlorinated biphenyls); (polychlorinated biphenyl);   (PCB's); (PCBs); (PCB); (polybrominated diphenyl ethers);   (polybrominated diphenyl ether); (PBDE's); (PBDE); (PBDEs);   (dichlorodiphenyltrichloroethane); (DDT); (pesticide); (pesticides);   (toxic organics); (toxic organic); (chemicals of concern); (chemical   of concern); (POP's); (POPs); (POP); (persistent organic chemicals);   (persistent organic chemical)

Status
In progress
Type
Project
Start Date
End Date
Scope of Study
Literature / Existing Data
Scale of Phenomena
Biochemical
Organism
Physical/Chemical
Population
Impact of Pollutants
Toxic Organics
Resource Management
Fisheries
Lake Basin Connecting Channels
Lake Erie
Lake Huron
Lake Michigan
Lake Ontario
Lake Superior
State Province
Wisconsin
Resource Being Monitored
Fisheries
Human Health
Beneficial Use Impairment Assessments
Restrictions of Fish and Wildlife Consumption
Tainting of Fish and Wildlife Populations
Annex Numbers
Persistent Toxic Substances
Research & Development
Specific Objectives for toxic substances and effluents
Annex 17
Population-based studies on long-term, low-level effects of toxic substances on human health
General
Monitoring
Annex
  • Annex Numbers
    Annex Numbers
    Persistent Toxic Substances
    Research & Development
    Specific Objectives for toxic substances and effluents
  • Annex 17
    Annex 17
    Population-based studies on long-term, low-level effects of toxic substances on human health

The Great Lakes - St. Lawrence Research Inventory is an
interactive, Internet-based, searchable database created as a tool to collect and disseminate
up-to-date information about research projects in the
Great Lakes - St. Lawrence Region.