The New York State Angler Cohort Study (NYSACS) is an epidemiologic investigation of risk perception, reproductive health and body burden of toxic chemicals associated with consumption of contaminated sport fish from Lake Ontario. The study addresses the need for a large population-based cohort study to assess the association between past and current consumption of contaminated fish and both short-term and long-term health effects. Keywords: Ah receptor,assessment,biomarker,cancer,consumption,fish, toxicity,health,native people,reproduction.
This research grant seeks to continue and expand mercury exposure research supported by the Agency for Toxic Substances and Disease Registry (ATSDR) Great Lakes Human Health Effects Research Program. This research effort will provide additional information needed regarding mercury exposure and possible health risks to women of childbearing age living in the Great Lakes Basin.
The study design is a cross-sectional and longitudinal observational assessment of the effects of PCB exposure, both current and in utero, on reproductive health. The main goal of this project is to assess fecundability and reproductive success in two cohort studies of individuals selected from two source populations at elevated risk of exposure to PCBs via consumption of Great Lakes sport-caught fish. A secondary goal is to pilot a case control study of low sperm count in relation to the same exposures.